Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma

·发布 2010年3月3日 ·更新 2015年4月29日

样本数

实验数

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相关文献

实验描述

Analysis of undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma-like tumors from LSL-KrasG12D, p53Fl/Fl mouse model of soft tissue sarcoma. Murine soft tissue sarcomas (n = 17) were compared to normal muscle (n = 4). Tumors were isolated surgically from soft tissue sarcomas generated by conditional Kras and p53 alleles. Tumors were induced using an adenovirus expressing Cre recombinase. Normal muscle samples were isolated from mice of the same genotype without tumor induction.

参考文献

Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma.

Mito JK, Riedel RF, Dodd L, Lahat G, Lazar AJ, Dodd RD, Stangenberg L, Eward WC, Hornicek FJ, Yoon SS, Brigman BE, Jacks T, Lev D, Mukherjee S, Kirsch DG

PMID: 19956606

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A-AFFY-36

Affymetrix GeneChip Mouse Genome 430A 2.0 [Mouse430A_2]（21 例）

样本属性

disease

conditional Kras and p53 mutation induced soft tissue sarcoma, normal

genotype

LSL-KrasG12D; Trp53Fl/Fl

organism

Mus musculus

organism part

muscle, soft tissue sarcoma

实验信息

登记号

E-GEOD-16779

GEO 编号

GSE16779

实验类型

transcription profiling by array

物种

Mus musculus

发布日期

2010年3月3日

更新日期

2015年4月29日

提交者

Rebecca D Dodd、 Tyler Jacks、 William C Eward、 Richard F Riedel、 Alexander J Lazar、 Jeffrey K Mito、 Leslie Dodd、 Sayan Mukherjee、 David G Kirsch、 Sam S Yoon、 Jeffrey Mito、 Lars Stangenberg、 Brian E Brigman、 Dina Lev、 Guy Lahat

外部链接

ArrayExpress 原始页 NCBI GEO：GSE16779

分析服务

Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma

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