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E-GEOD-22396 GSE22396 transcription profiling by array Homo sapiens

Gene expression analysis of Merkel Cell Carcinoma

·发布 2010年12月15日 ·更新 2012年3月2日
35
样本数
35
实验数
1
芯片平台
实验描述

Merkel cell carcinoma (MCC) is a polyomavirus-associated skin cancer that is frequently lethal and lacks established prognostic biomarkers. The purpose of this study was to use gene expression analysis to identify biomarkers that may improve prognostic accuracy and provide insight into MCC biology. We profiled 35 tumors from 34 patients. Tumors were macrodissected from surrounding stroma. RNA isolation was performed with RNeasy or Allprep Mini kits (Qiagen, Alameda, CA), and RNA quality assessed by Agilent Bioanalyzer analysis. RNAs were profiled on the Human Rosetta Custom Affymetrix 2.0 chip.

芯片平台
A-GEOD-10379
Rosetta/Merck Human RSTA Custom Affymetrix 2.0 microarray(35 例)
样本属性
age
44 year old, 45 year old, 47 year old, 54 year old, 55 year old, 58 year old, 60 year old, 63 year old, 64 year old, 65 year old, 66 year old, 67 year old, 70 year old, 73 year old, 74 year old, 75 year old, 77 year old, 78 year old, 80 year old, 85+ year old, unknown
Organism
Homo sapiens
sample type
Merkel cell carcinoma metastasis tumor RNA (macrodissected, includes stroma) from a 45 year old, Merkel cell carcinoma metastasis tumor RNA (macrodissected, includes stroma) from a 58 year old, Merkel cell carcinoma nodal metastasis tumor RNA (macrodissected, includes stroma) from a male patient with poor prognosis (progression to distant met), Merkel cell carcinoma nodal metastasis tumor RNA (macrodissected, includes stroma) from a 63 year old, Merkel cell carcinoma nodal metastasis tumor RNA (macrodissected, includes stroma) from a 65 year old, Merkel cell carcinoma nodal metastasis tumor RNA (macrodissected, includes stroma) from a 66 year old, Merkel cell carcinoma nodal metastasis tumor RNA (macrodissected, includes stroma) from a 70 year old, Merkel cell carcinoma primary tumor RNA (macrodissected, from wide local excision, includes stroma) from a 65 year old, Merkel cell carcinoma primary tumor RNA (macrodissected, includes stroma) from a 60 year old, Merkel cell carcinoma primary tumor RNA (macrodissected, includes stroma) from a 70 year old, Merkel cell carcinoma primary tumor RNA (macrodissected, includes stroma) from a 73 year old, Merkel cell carcinoma primary tumor RNA (macrodissected, includes stroma) from a 74 year old, Merkel cell carcinoma primary tumor RNA (macrodissected, includes stroma) from a 77 year old, Merkel cell carcinoma primary tumor RNA (macrodissected, includes stroma) from a 78 year old, Merkel cell carcinoma primary tumor RNA (macrodissected, includes stroma) from an 85+ year old, Merkel cell carcinoma recurrence tumor RNA (macrodissected, includes stroma) from a 47 year old, Merkel cell carcinoma recurrence tumor RNA (macrodissected, includes stroma) from a 66 year old, Merkel cell carcinoma skin metastasis (regional) tumor RNA (macrodissected, includes stroma) from a 80 year old, Merkel cell carcinoma skin metastasis tumor RNA (macrodissected, includes stroma) from a 54 year old, Merkel cell carcinoma skin metastasis tumor RNA (macrodissected, includes stroma) from a 75 year old, Merkel cell carcinoma skin metastasis tumor RNA (macrodissected, includes stroma) from a74 year old, Merkel cell carcinoma tumor RNA (macrodissected, includes stroma) from a 44 year old, Merkel cell carcinoma tumor RNA (macrodissected, includes stroma) from a 55 year old, Merkel cell carcinoma tumor RNA (macrodissected, includes stroma) from a 63 year old, Merkel cell carcinoma tumor RNA (macrodissected, includes stroma) from a 64 year old, Merkel cell carcinoma tumor RNA (macrodissected, includes stroma) from a 67 year old, Merkel cell carcinoma tumor RNA (macrodissected, includes stroma) from a 74 year old, Merkel cell carcinoma tumor RNA (macrodissected, includes stroma) from a 77 year old, Merkel cell carcinoma tumor RNA (macrodissected, includes stroma) from a 85+ year old, Merkel cell carcinoma tumor RNA (macrodissected, includes stroma) from a male patient with poor prognosis (progression to distant met), Merkel cell carcinoma tumor RNA (recurrence, macrodissected, includes stroma) from a 73 year old, SAME PATIENT AS 63975_w200p: Merkel cell carcinoma nodal metastasis tumor RNA (macrodissected, includes stroma) from a 60 year old
tissue
Merkel cell carcinoma metastasis tumor, Merkel cell carcinoma nodal metastasis tumor, Merkel cell carcinoma primary tumor, Merkel cell carcinoma recurrence tumor, Merkel cell carcinoma skin metastasis (regional) tumor, Merkel cell carcinoma skin metastasis tumor, Merkel cell carcinoma tumor
实验信息
登记号
E-GEOD-22396
GEO 编号
GSE22396
实验类型
transcription profiling by array
物种
Homo sapiens
发布日期
2010年12月15日
更新日期
2012年3月2日
提交者
Paul Nghiem、 Michele Cleary、 Michele A Cleary、 Janell Schelter、 Kelly G Paulson、 Jayasri G Iyer、 James Hardwick
分析服务
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