Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia

·发布 2012年10月16日 ·更新 2012年10月22日

样本数

实验数

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相关文献

实验描述

Transcriptome profile of highly purified multipotential (P), erythroid (E), and myeloid (M) bone marrow progenitors from three RPS19 mutated Diamond-Blackfan anemia and six control human subjects. Two group comparison of sex and age matched subjects. Bone marrow progenitors, gene expression profiling, Diamond-Blackfan anemia, RPS19

参考文献

Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia.

Gazda HT, Kho AT, Sanoudou D, Zaucha JM, Kohane IS, Sieff CA, Beggs AH

PMID: 16741228

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A-AFFY-33

Affymetrix GeneChip Human Genome HG-U133A [HG-U133A]（27 例）

样本属性

age

30 year old, 42 year old, 46 year old, between 25 and 40 years old

cell type

erythroid E, CD34+, CD71 hi, CD45RA−, multipotential P, CD34+, CD71−, CD45RA−, myeloid M, CD34+, CD71 low, CD45RA+

disease status

control, Diamond–Blackfan anemia

Organism

Homo sapiens

Sex

female, male

subject id

C1, C2, C3, C4, C5, C6, D1, D2, D3

实验信息

登记号

E-GEOD-41599

GEO 编号

GSE41599

实验类型

transcription profiling by array

物种

Homo sapiens

发布日期

2012年10月16日

更新日期

2012年10月22日

提交者

Alvin T. Kho、 Alvin T Kho、 Hanna T Gazda

外部链接

ArrayExpress 原始页 NCBI GEO：GSE41599

分析服务

Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia

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