Transcription profiling of mouse model of endometrioid ovarian adenocarcinomas by conditional inactivation of the PTEN and APC genes

Fifty million plaque-forming units of AdCre was injected into the right ovarian bursal cavity of 56- 70 day old female mice. Mice were euthanized 63 days later to obtain ovary tumors and normal ovary tissue. Seven individual ovarian tumors and 4 individual normal ovary samples were each assayed on an Affymetrix Mouse Genome 430 2.0 array. Experiment Overall Design: 7 individual ovarian tumors and 4 individual normal ovary samples. RNA expression was analyzed using one Affymetrix Mouse Genome 430 2.0 array per sample.