Transcription profiling of mouse wild type (wt) and Ikbke knockout (Ikke) embryonic fibroblasts (EF)

WT and Ikbke-/- EF cells were stimulated with recombinant interferon beta for 6 hours. Cells lacking IKKe kinase show a defect in a subset of interferon stimulated gene transcription Experiment Overall Design: WT and Ikbke cells were either stimulated and left untreated to compare their response to interferon.