Transcription profiling of macrophages from Familial Hypercholesterolemia(FH) patients with tendon xanthomas (TX+) and without tendon xanthomas (TX-) to evaluate the gene expression profile in presence and absence of oxidized LDL

·发布 2006年1月1日 ·更新 2014年5月3日

样本数

实验数

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相关文献

实验描述

Total RNA pools from macrophages from Familial Hypercholesterolemia(FH) patients with tendon xanthomas (TX+) and without tendon xanthomas (TX-) were analyzed using Affymetrix oligonucleotide arrays (HGU133A) to evaluate the gene expression profile in presence and absence of oxidized LDL.

参考文献

Tendon xanthomas in familial hypercholesterolemia are associated with a differential inflammatory response of macrophages to oxidized LDL

Marta Artieda; Ana Cenarro; Corina Junquera; Pilar Lasierra; Maria Jose Martinez-Lorenzo; Miguel Pocovi; Fernando Civeira

PMID: 16083882

芯片平台

A-AFFY-33

Affymetrix GeneChip Human Genome HG-U133A [HG-U133A]（4 例）

样本属性

BioSourceType

blood

ClinicalInformation

LDLox+, LDLox-

DiseaseState

no tendon xanthomas, tendon xanthomas

IndividualGeneticCharacteristics

heterozygous familial hypercholesterolemia

Organism

Homo sapiens

OrganismPart

peripheral blood

TargetedCellType

monocyte-derived macrophages

实验信息

登记号

E-MEXP-360

实验类型

transcription profiling by array

物种

Homo sapiens

发布日期

2006年1月1日

更新日期

2014年5月3日

提交者

Pilar Lasierra、 Miguel Pocovi、 Maria Jose Martinez-Lorenzo、 Marta Artieda、 Fernando Civeira、 Corina Junquera、 Ana Cenarro

外部链接

ArrayExpress 原始页

分析服务

Transcription profiling of macrophages from Familial Hypercholesterolemia(FH) patients with tendon xanthomas (TX+) and without tendon xanthomas (TX-) to evaluate the gene expression profile in presence and absence of oxidized LDL

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