Single Cell Multi-Omics of Human Preimplantation Embryos Demonstrates Susceptibility to Excess Glucocorticoid Exposure (small RNA part)

We then utilized parallel single-cell RNA sequencing and bisulfite sequencing to explore the impact of GC exposure on the human embryo. In addition, to further explore the role of epigenetic regulation as a mechanism for the observed transcriptional changes, we examined the effects of GCs on small non-coding RNA using smallseq.