Single-cell RNA-seq comparing WT, HDAC3 and Dax1 knock-out clones in SL(RA) differentiation conditions

·发布 2021年3月15日

样本数

实验数

相关文献

实验描述

We performed single-cell RNA-seq in order to characterize in high resolution the transcriptomic profiles, differentiation fates and heterogeneity of wild-type, HDAC3 or Dax1 knock-out cells in SL(RA) differentiation conditions.

参考文献

Mechanistic framework of lineage restriction in embryonic stem cells

Daniel Olivieri, Panagiotis Papasaikas, Ilya Lukonin, Melanie Rittirsch, Daniel Hess, Sebastien Smallwood, Michael B. Stadler and Joerg Betschinger

样本属性

Organism

Mus musculus

Developmental stage

mouse embryo stage

Cell type

mouse embryonic stem cell

Disease

normal

Cell line

TNG-A (cl7), TNG-A (cl2), TNG-A (WT1 parental)

Genotype

DAX1 -/-, HDAC3 -/-, wild type genotype

实验信息

登记号

E-MTAB-10147

实验类型

RNA-seq of coding RNA from single cells

物种

Mus musculus, Mus musculus

发布日期

2021年3月15日

提交者

Panagiotis Papasaikas、 Joerg Betschinger、 Daniel Olivieri

外部链接

ArrayExpress 原始页

分析服务

Single-cell RNA-seq comparing WT, HDAC3 and Dax1 knock-out clones in SL(RA) differentiation conditions

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