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E-MTAB-10150 RNA-seq of coding RNA Mus musculus, Mus musculus

RNA-seq comparing WT to HDAC3 and Dax1 knock-out clones in cell-sorted populations in 2iLIF and SL(RA) differentiation conditions

·发布 2021年3月15日
24
样本数
24
实验数
1
相关文献
实验描述

In order to determine the transcriptomic profiles of PrE-induced cells following HDAC3 or Dax1 knock-out in SL(RA) differentiation conditions, RNA-seq was performed on Gata6+ or Nanog+ sort-selected cells. Profiles are contrasted with WT cells in the same differentiation conditions as well as to mock-sorted populations of the three genotypes in 2iLIF conditions.

参考文献
Cooperation between HDAC3 and DAX1 mediates lineage restriction of embryonic stem cells
Olivieri D, Castelli E, Kawamura YK, Papasaikas P, Lukonin I, Rittirsch M, Hess D, Smallwood SA, Stadler MB, Peters AHFM, Betschinger J
PMID: 33909924
样本属性
Organism
Mus musculus
Developmental stage
mouse embryo stage
Cell type
mouse embryonic stem cell
Cell line
TNG-A
Disease
normal
Genotype
wild type genotype, DAX1 -/-, HDAC3 -/-
Growth condition
2iL, SL
Phenotype
mock sort, GATA6+ Nanog-, Nanog+ GATA6-
实验信息
登记号
E-MTAB-10150
实验类型
RNA-seq of coding RNA
物种
Mus musculus, Mus musculus
发布日期
2021年3月15日
提交者
Daniel Olivieri、 Joerg Betschinger、 Panagiotis Papasaikas
分析服务
分析服务

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