Bulk RNA-seq of archived Acute Myeloid Leukemia (AML) samples propagated in a mouse Xenograft model over several passages

·发布 2021年8月1日

样本数

实验数

相关文献

实验描述

Cryopreserved AML PDX samples were collected with minimal harm to the sample by taking a biopsy punch from the vial of cell and transfering it into lysis buffer. 96 AML PDX samples collected in such manner were processed using prime-seq to generate high quality expression profiles.

参考文献

prime-seq, a simple, inexpensive, and powerful bulk RNA-sequencing protocol for detecting differential expression

Aleksandar Janjic, Lucas E. Wange, Johannes W. Bagnoli, Johanna Geuder, Phong Nguyen, Daniel Richter, Beate Vieth, Christoph Ziegenhain, Binje Vick, Ines Hellmann, Wolfgang Enard

样本属性

Organism

Homo sapiens

Developmental stage

adult

Disease

acute myeloid leukemia

Organism part

bone marrow

Cell type

AML blast

Cell line

AML579, AML388, AML393, AML491, AML573, AML602, AML372, AML407, AML361, AML538, AML415

Genotype

NPM1/FLT3-ITD, complex karyotype, MLL rearranged, not favourable nor adverse, CN

Passage

4, 7, 0, 1, 6, 2, 5, 9, 10, 3, 8

Passage_bin

Early Passage(1-3), Late Passage(>4), Initial Passage(0)

Sample barcode

AAAACT, AAAGTT, AAATTG, ... 93 other values

实验信息

登记号

E-MTAB-10175

实验类型

Cell line - High-throughput sequencing, RNA-seq of coding RNA

物种

Homo sapiens, Homo sapiens

发布日期

2021年8月1日

提交者

Lucas Esteban Wange、 Aleksandar Janjic

外部链接

ArrayExpress 原始页

分析服务

Bulk RNA-seq of archived Acute Myeloid Leukemia (AML) samples propagated in a mouse Xenograft model over several passages

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