Single-cell RNA-seq of Endometrial Superficial biopsies and full depth uterine tissue from organ donors

·发布 2021年7月21日

样本数

实验数

相关文献

实验描述

We performed single-cell RNA-sequencing to create a cell census of the human endometrium, which is the mucosal lining of the uterus that undergoes dynamic changes throughout the menstrual cycle. We integrated cells that were obtained from 3 superficial biopsies to selected samples that originated from 2 organ donors; this allowed a better representation of cell type diversity found within the full depth of the endometrium.

参考文献

Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

Luz Garcia-Alonso, Louis-François Handfield, Kenny Roberts, Konstantina Nikolakopoulou, Ridma C. Fernando, Lucy Gardner, Ben Woodhams, Anna Arutyunyan, Krzysztof Polanski, Regina Hoo, Carmen Sancho-Serra, Tong Li, Kwasi Kwakwa, Elizabeth Tuck, Vitalii Kleshchevnikov, Aleksandra Tarkowska, Tarryn Porter, Cecilia Icoresi Mazzeo, Stijn van Dongen, Monika Dabrowska, Vasyl Vaskivskyi, Krishna T. Mahbubani, Jong-eun Park, Mercedes Jimenez-Linan, Lia Campos, Vladimir Kiselev, Cecilia Lindskog, Paul Ayuk, Elena Prigmore, Michael R Stratton, Kourosh Saeb-Parsy, Ashley Moffett, Luiza Moore, Omer A. Bayraktar, Sarah A. Teichmann, Margherita Y. Turco, Roser Vento-Tormo

样本属性

Organism

Homo sapiens

Sex

female

Developmental stage

adult

Individual

E1, E2, A13, E3, A30

Organism part

endometrium, myometrium

Menstrual cycle stage

proliferative stage, early-secretory stage, late-secretory stage, mid-secretory stage

Digestion treatment

collagenase, trypsin

实验信息

登记号

E-MTAB-10287

实验类型

RNA-seq of coding RNA from single cells, Human - Single-cell sequencing, baseline

物种

Homo sapiens, Homo sapiens

发布日期

2021年7月21日

提交者

Louis-Francois Handfield

外部链接

ArrayExpress 原始页

分析服务

Single-cell RNA-seq of Endometrial Superficial biopsies and full depth uterine tissue from organ donors

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