Actinomycin D-induced mitochondrial stress targets PML during NPM1c-AML therapy

·发布 2021年5月10日

样本数

实验数

芯片平台

相关文献

实验描述

Microarrays transcriptomic data analyses from acute myeloid leukemia cell line OCI-AML2 and primary acute myeloid leukemia cells treated with actinomycin D.

参考文献

Actinomycin D-induced mitochondrial stress targets PML during NPM1c-AML therapy

Hsin Chieh Wu, Domitille Rérolle, Caroline Berthier, Rita Hleihel, Samuel Quentin, Shirine Benhenda, Claudia Morganti, Chengchen Wu, Lidio Conte, Marie Sebert, Emmanuelle Clappier, Sylvie Souquere, Stéphanie Gachet, Jean Soulier, Sylvère Durand, Jennifer Trowbridge, Paule Benit, Pierre Rustin, Hiba El Hajj, Emmanuel Raffou, Lionel Ades, Raphael Itzykson, Hervé Dombret, Pierre Fenaux, Guido Kroemer, Lorenzo Brunetti, Valérie Lallemand-Breitenbach, Ali Bazarbachi, Brunangelo Falini, Keisuke Ito, Maria Paola Martelli & Hugues de Thé

芯片平台

A-GEOD-20932

[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 (CDF: hta20hsensgcdf_19.0.0.cdf, version 19)（22 例）

样本属性

Organism

Homo sapiens

Disease

acute myeloid leukemia

Organism part

blood

Cell line

OCI-AML2, primary cell

Replicate

1, 2

Genotype

NPM1 WT, NPM1 mutant

Cell type

OCI-AML2, Primary leukemia blasts

实验信息

登记号

E-MTAB-10397

实验类型

Human - One-color microarray, transcription profiling by array

物种

Homo sapiens, Homo sapiens

发布日期

2021年5月10日

提交者

Samuel QUENTIN、 Hugues De Thé、 Hsin-Chieh Wu

外部链接

ArrayExpress 原始页

分析服务

Actinomycin D-induced mitochondrial stress targets PML during NPM1c-AML therapy

联系地址

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