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E-MTAB-10729 Cell line - High-throughput sequencing,… Mus musculus, Mus musculus

In vivo CRISPR screen targeting TSGs in 185-3 MPNST cells

·Released Oct. 1, 2021
34
Samples
136
Assays
Description

185-3 MPNST cells cells were screened with a CRISPR library against TSGs in vitro and as tumors in Rag1-null and immunocompetent WT C57BL/6 mice

Sample Attributes
Organism
Mus musculus
Strain
129/sv × C57BL/6
Developmental stage
embryo
Organism part
inner cell mass
Genotype
Nf1 +/−; p53 +/−
Genetic modification
CRISPR library against TSGs
Disease
malignant peripheral nerve sheath tumor
Cell line
185-3
Growth condition
injection until tumour growth in wild type genotype mice, in vitro, injection until tumour growth in Rag1 -/- mice
Experiment Info
Accession
E-MTAB-10729
Type
Cell line - High-throughput sequencing, DNA-seq
Organism
Mus musculus, Mus musculus
Released
Oct. 1, 2021
Submitter
Timothy Martin
External Links
ArrayExpress source
Analysis Services
Analysis Services

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