Nanostring analysis of exosomal miRNA from plasma of head and neck cancer (HNSCC) patients

·Released Nov. 9, 2022

Samples

Assays

Array Platforms

Description

Exosomes were isolated from plasma of n = 12 healthy donors (HD) and n = 16 head and neck cancer (HNSCC) patients. miRNA profiling of exosomes was performed using nCounter SPRINT system. miRNAs being predicted to target EMT-related genes (CDH1, VIM, TWIST1 and SNAI1/2) were selected and compared between HD and HNSCC patients.

Array Platforms

A-GEOD-14822

NanoString nCounter Human miRNA assay（28 items）

Sample Attributes

Organism

Homo sapiens

Developmental stage

adult

Organism part

blood plasma

Fraction

exosome

Age

62 year, 73 year, 75 year, 66 year, 59 year, 77 year, 68 year, 61 year, 56 year, 79 year, 52 year, 69 year, 63 year, 53 year, 58 year, ... 2 other values

Sex

female, male

Disease

normal, head and neck squamous cell carcinoma

Disease staging

tumor grading I (low), none, tumor grading IV (high), tumor grading III (high)

Experiment Info

Accession

E-MTAB-12408

Type

microRNA profiling by array

Organism

Homo sapiens, Homo sapiens

Released

Nov. 9, 2022

Submitter

Linda Hofmann

External Links

ArrayExpress source

Analysis Services

Nanostring analysis of exosomal miRNA from plasma of head and neck cancer (HNSCC) patients

Contact

WeChat Official Account