Gene expression data from preadipocytes (i.e., adipocyte progenitor cells, APCs) in ICR mice under conditions of early-onset and high-fat diet (HFD)-induced obesity.

During obesity, white adipose tissue (WAT) expands to accommodate excess energy storage. Adipocytes and non-adipocyte cells, including preadipocytes/adipocyte progenitor cells, participate in a coordinated process to remodel and expand WAT. We used microarrays to profile gene expression in preadipocytes/APCs during early-onset and HFD-induced obesity, revealing distinct depot-specific pathways associated with each condition.