Collagen-binding C-type natriuretic peptide enhances chondrogenesis and osteogenesis

·发布 2025年12月5日

样本数

实验数

相关文献

实验描述

To enhance local drug delivery and therapeutic efficacy, we developed a novel synthetic protein by fusing a collagen-binding domain (CBD) to C-type natriuretic peptide (CNP), termed CBD-CNP. CBD-CNP localized to collagen-rich tissues and promoted bone elongation.

参考文献

Collagen-binding C-type natriuretic peptide enhances chondrogenesis and osteogenesis

Kenta Hirai, Kenta Sawamura, Ryusaku Esaki, Ryusuke Sawada, Yuka Okusha, Eriko Aoyama, Hiroki Saito, Kentaro Uchida, Takehiko Mima, Satoshi Kubota, Hirokazu Tsukahara1, Shiro Imagama, Masaki Matsushita, Osamu Matsushita, Yasuyuki Hosono

样本属性

Organism

Mus musculus

Developmental stage

embryonic day 16.5

Organism part

right tibia, left tibia

Individual

Cont-vs-Fgf2, Fgf2-vs-CBD-CNP

实验信息

登记号

E-MTAB-16154

实验类型

spatial transcriptomics by high-throughput sequencing

物种

Mus musculus, Mus musculus

发布日期

2025年12月5日

提交者

Ryusuke Sawada、 Kenta Hirai

外部链接

ArrayExpress 原始页

分析服务

Collagen-binding C-type natriuretic peptide enhances chondrogenesis and osteogenesis

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