micro RNA profiling by array of KIT/PDGFRA mutant and wild type gastrointestinal stromal tumors

提交 2015年11月10日 ·发布 2016年10月3日 ·更新 2017年3月22日

样本数

实验数

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相关文献

实验描述

A growing body of literature has consolidated the important role of miRNA in a variety of biological processes, in cancer development, acting both as oncogenes and tumor suppressor genes, and in their ability to distinguish tumors according to their diagnostic and prognostic properties.To date, little is known, however, about differences in miRNA expression between KIT/PDGFRA mutant and KIT/PDGFRA WT GIST.

参考文献

Integrating miRNA and gene expression profiling analysis revealed regulatory networks in gastrointestinal stromal tumors.

Pantaleo MA, Ravegnini G, Astolfi A, Simeon V, Nannini M, Saponara M, Urbini M, Gatto L, Indio V, Sammarini G, Santini D, Ferracin M, Negrini M, Hrelia P, Biasco G, Angelini S.

PMID: 27625077

芯片平台

A-MEXP-1663

Agilent Human miRNA G4470B (019118)（13 例）

样本属性

cancer site

localized, metastatic

disease

gastrointestinal stromal tumor

genetic modification

mutation in KIT or PDGFRA, wild type genotype

genotype

KIT exon 11 del WK557-558, KIT exon 11 ins TQLPYDHKWEFP574-585 at P585, KIT exon 11 V559D, KIT exon 11 V560D, KIT exon 9 ins AY502-503, KIT/PDGFRA wild type, SDH deficient, PDGFRA exon 12 del/ins SPDGHE566-571RIQ, PDGFRA exon 14 K646E, PDGFRA exon 18 del DIMH842-845

organism

Homo sapiens

organism part

small intestine, stomach

实验信息

登记号

E-MTAB-4490

实验类型

microRNA profiling by array

物种

Homo sapiens

提交日期

2015年11月10日

发布日期

2016年10月3日

更新日期

2017年3月22日

提交者

Sabrina Angelini、 Vittorio Simeon

外部链接

ArrayExpress 原始页

分析服务

micro RNA profiling by array of KIT/PDGFRA mutant and wild type gastrointestinal stromal tumors

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