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E-MTAB-5708 ERP022747 RNA-seq of coding RNA Mus musculus

RNA-Seq of pancreatic islets from beta cell-specific Pax6 knockout mice

Submitted Feb. 8, 2017 ·Released April 26, 2017 ·Updated April 26, 2017
9
Samples
9
Assays
1
References
Description

RNA-Seq to investigate significant transcriptional differences underlying the defective glucose-stimulated insulin secretion of Pax6 knockout mice in comparison to floxed littermate controls.

References
The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis and Ca2+ dynamics in adult mice
Mitchell RK, Nguyen-Tu MS, Chabosseau P, Callingham RM, Pullen TJ, Cheung R, Leclerc I, Hodson DJ, Rutter GA
PMID: 28377501
Sample Attributes
age
10 week
genotype
Pax6 fl/fl, Pdx1-CreERT / Pax6 fl/fl
organism
Mus musculus
organism part
islet of Langerhans
phenotype
beta cell specific Pax6 knockout, wild type
sex
female, male
strain
C57BL/6
Experiment Info
Accession
E-MTAB-5708
GEO ID
ERP022747
Type
RNA-seq of coding RNA
Organism
Mus musculus
Submitted
Feb. 8, 2017
Released
April 26, 2017
Updated
April 26, 2017
Submitter
Timothy Pullen、 Guy Rutter
External Links
ArrayExpress source NCBI GEO：ERP022747
Analysis Services
Analysis Services

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