RNA seq experiment of Treg cells isolated from peripheral blood of patients with pulmonary sarcoidosis compared to Treg cells from peripheral blood of healthy individuals

提交 2016年3月1日 ·发布 2018年9月29日 ·更新 2017年10月24日

样本数

实验数

相关文献

实验描述

Sarcoidosis is manifested by an exaggerated Th1 response on one hand, combined with high numbers of dysfunctional Treg cells on the other3. Moreover, it has been shown that Treg cells in patients with pulmonary sarcoidosis (PS) have impaired immunosuppressive function, survival and enhanced apoptotic susceptibility towards Fas ligand (CD95L)4. However, the molecular background for the impairment of the Treg function in PS has not been elucidated.

参考文献

Molecular profiling of regulatory T cells in pulmonary sarcoidosis.

Kachamakova-Trojanowska N, Jazwa-Kusior A, Szade K, Kasper L, Soja J, Andrychiewicz A, Jakiela B, Plutecka H, Sanak M, Jozkowicz A, Sladek K, Dulak J.

PMID: 30049532

样本属性

age

26 year, 31 year, 36 year, 37 year, 38 year, 40 year, 42 year, 50 year, 58 year, 60 year

cell type

regulatory T cell

disease

normal, pulmonary sarcoidosis

organism

Homo sapiens

organism part

blood

phenotype

CD4+/CD25+/CD127-

sex

female, male

实验信息

登记号

E-MTAB-6158

GEO 编号

ERP104908

实验类型

RNA-seq of coding RNA

物种

Homo sapiens

提交日期

2016年3月1日

发布日期

2018年9月29日

更新日期

2017年10月24日

提交者

Neli Kachamakova-Trojanowska

外部链接

ArrayExpress 原始页 NCBI GEO：ERP104908

分析服务

RNA seq experiment of Treg cells isolated from peripheral blood of patients with pulmonary sarcoidosis compared to Treg cells from peripheral blood of healthy individuals

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