ChIP-seq of Pbx1, Prep1 and Sp2 in WT MEFs, Sp2ko MEFs and in Sp2ko MEFs ectopically expressing Flag-tagged full length Sp2; and ChIPexo of Sp2 in WT and Sp2ko MEFs

·Released Oct. 17, 2018 ·Updated Oct. 17, 2018

Samples

Assays

References

Description

We investigated the genomic binding profiles of the transcription factors Pbx1, Prep1, and Sp2 in mouse embryonic fibroblasts using ChIPseq and ChIPexo. Refer to E-MTAB-2970 and E-MTAB-994 for KO and IgG Controls.

References

Transcription factor Sp2 potentiates binding of the TALE homeoproteins Pbx1:Prep1 and the histone-fold domain protein Nf-y to composite genomic sites.

Völkel S, Stielow B, Finkernagel F, Berger D, Stiewe T, Nist A, Suske G.

PMID: 30337366

Sample Attributes

cell type

mouse embryonic fibroblast cell

developmental stage

embryo

disease

normal

genotype

Sp2 homozygous knockout, Sp2 homozygous knockout; Sp2-FLAG, wild type genotype

organism

Mus musculus

organism part

embryo

Experiment Info

Accession

E-MTAB-7125

GEO ID

ERP110324

Type

ChIP-seq

Organism

Mus musculus

Released

Oct. 17, 2018

Updated

Oct. 17, 2018

Submitter

Florian Finkernagel、 Guntram Suske

External Links

ArrayExpress source NCBI GEO：ERP110324

Analysis Services

ChIP-seq of Pbx1, Prep1 and Sp2 in WT MEFs, Sp2ko MEFs and in Sp2ko MEFs ectopically expressing Flag-tagged full length Sp2; and ChIPexo of Sp2 in WT and Sp2ko MEFs

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