Expression profile of A459 cells upon LKB1 expression

The purpose of the experiment is to study the expression profiles variations upon the expression of the wild type isoform of LKB1 (STK11) in human lung carcinoma A459 cells. These cells are KRAS mutated and null for STK11. Cells were previously infected with the lentiviral construct pLenti-rtTA2-IRES-H2B-GFP doxycycline-inducible plasmid (obtained from S. Tenbaum, HG Palmer’s Lab Vall d´Hebron Institute of Oncology, VHIO) containing the human STK11wild type cDNA.