CCT4P1 (chaperonin containing TCP1 subunit 4 pseudogene 1)

Gene Basic Information

Gene Basic Information

symbol:
CCT4P1
locus group:
pseudogene
location:
7q34
gene_family:
alias symbol:
None
alias name:
None
entrez id:
650172
ensembl gene id:
ENSG00000242703
ucsc gene id:
None
refseq accession:
NG_016595
hgnc_id:
HGNC:35151
approved reserved:
2008-09-22

Chromosome Location

Chromosome Location

7q34

Gene Summary

Gene Summary

CCT4P1是一个假基因，属于CCT（伴侣蛋白含TCP-1）基因家族。CCT基因家族编码分子伴侣蛋白，主要功能是协助蛋白质的正确折叠和组装，尤其在细胞骨架蛋白如肌动蛋白和微管蛋白的折叠过程中起关键作用。CCT家族成员通常形成多亚基复合物，通过ATP依赖的方式帮助新生肽链折叠。CCT4P1作为假基因，可能由CCT4基因复制产生，但由于突变积累丧失了编码功能蛋白的能力。假基因通常不表达或产生非功能性RNA，但某些情况下可能通过竞争性结合miRNA或转录因子来调控其同源基因的表达。目前关于CCT4P1的具体功能研究较少，假基因的突变或表达变化一般不会直接影响机体，但可能通过调控网络间接影响CCT家族功能。CCT家族成员（如CCT1-8）的异常表达与神经退行性疾病、癌症等相关，因其错误折叠蛋白的积累会导致细胞功能障碍。若CCT4P1异常表达，可能干扰CCT4的正常调控，影响蛋白质稳态，但具体机制尚不明确。该基因的研究有助于理解假基因的进化及在疾病中的潜在调控作用。

ChineseEnglish

None

OMIM entry for CCT4P1     Wikipedia entry for CCT4P1

Gene Sequence

Gene Sequence

Nucleotide sequence of CCT4P1:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of CCT4P1:           Showing partial SNPs

Gene Expression

Gene Expression

Tissue expression of CCT4P1:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
CATACAGTCATAAACTTGGTGG
57
GGTTATGCCAGAATTTACCAC
57
CATACAGTCATAAACTTGGTGG
57
GCCAGAATTTACCACTTTCTG
58
CATACAGTCATAAACTTGGTGG
57
GAATTTACCACTTTCTGGGTG
57

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of CCT4P1 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for CCT4P1:

Related microRNA

Related microRNA

microRNAs potentially regulating CCT4P1:     

Gene Interactions

Gene Interactions

Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

No related publications

Related Services

Related Services

Comments

Comments

Loading comments...

Log in to post comments Log In Sign Up

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2