DAP3P1 (death associated protein 3 pseudogene 1)

Gene Basic Information

Gene Basic Information

symbol:
DAP3P1
locus group:
pseudogene
location:
1q22
gene_family:
alias symbol:
MRPS29P1
alias name:
mitochondrial ribosomal protein S2…
entrez id:
359804
ensembl gene id:
ENSG00000225082
ucsc gene id:
None
refseq accession:
NG_002904
hgnc_id:
HGNC:17624
approved reserved:
2006-03-22

Chromosome Location

Chromosome Location

1q22

Gene Summary

Gene Summary

DAP3P1（Death Associated Protein 3 Pseudogene 1）是一个假基因，属于DAP基因家族的成员之一。假基因通常是由功能基因复制或逆转录而来，但由于突变积累而失去编码功能蛋白的能力。DAP基因家族主要与细胞凋亡（程序性细胞死亡）相关，其成员如DAP3在调控线粒体介导的凋亡通路中发挥重要作用。DAP3P1作为假基因，目前尚未发现其编码功能性蛋白的证据，但它可能通过调控其他基因的表达或作为竞争性内源RNA（ceRNA）影响细胞功能。由于假基因的突变通常不会直接影响机体功能，但某些情况下可能通过干扰相关功能基因的表达或调控网络间接发挥作用。DAP3P1的过表达或降低表达可能影响其同源功能基因（如DAP3）的表达水平，从而间接干扰细胞凋亡等生物学过程。目前关于DAP3P1与疾病关系的研究较少，但假基因的异常表达或突变在某些癌症中可能通过调控网络影响肿瘤发生发展。DAP基因家族的共性在于它们多与细胞凋亡、自噬等细胞死亡过程相关，部分成员还参与免疫调节和炎症反应。由于DAP3P1是假基因，其生物学意义仍需进一步研究以明确其在基因组中的潜在调控作用。

OMIM entry for DAP3P1     Wikipedia entry for DAP3P1

Gene Sequence

Gene Sequence

Nucleotide sequence of DAP3P1:[NCBI]
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Gene Variants

Gene Variants

SNP variants of DAP3P1:           Showing partial SNPs

Gene Expression

Gene Expression

Tissue expression of DAP3P1:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
ATTCCAGATGCTCATCTTTGG
59
AAGGTTGATCAAAGCGCTG
59
TCCAGATGCTCATCTTTGGG
60
TAAAGGTTGATCAAAGCGCTG
60
TCCAGATGCTCATCTTTGGG
60
AAAGGTTGATCAAAGCGCTG
60

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of DAP3P1 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for DAP3P1:

Related microRNA

Related microRNA

microRNAs potentially regulating DAP3P1:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

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Related Publications

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