MIR103A1 (microRNA 103a-1)

Gene Basic Information

Gene Basic Information

symbol:
MIR103A1
locus group:
non-coding RNA
location:
5q34
gene_family:
MicroRNAs
alias symbol:
hsa-mir-103-1|hsa-mir-103a-1
alias name:
None
entrez id:
406895
ensembl gene id:
ENSG00000199035
ucsc gene id:
uc003maa.3
refseq accession:
NR_029520
hgnc_id:
HGNC:31490
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

5q34

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR103A1     Wikipedia entry for MIR103A1

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR103A1:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR103A1:           Showing partial SNPs
rs2124880       rs11952767       rs17664767       rs76828494       rs77105202       rs77612793       rs78909266       rs79933722       rs111979725       rs113088513       rs113156059       rs139722029       rs142714349       rs143050117       rs183853373       rs185132241       rs187817721      

Gene Expression

Gene Expression

Tissue expression of MIR103A1:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
CGGCTTCTTTACAGTGCTG
59
TCATAGCCCTGTACAATGC
57
CTCGGCTTCTTTACAGTGC
58
ATAGCCCTGTACAATGCTG
57
TCGGCTTCTTTACAGTGCT
59
CATAGCCCTGTACAATGCTG
58

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR103A1 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR103A1:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR103A1:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Transient Ischemic Attack 0.000271442 1 0 BeFree
Brain Ischemia 0.000271442 1 0 BeFree
Cerebrovascular accident 0.000271442 1 0 BeFree
Transient Cerebral Ischemia 0.000271442 1 0 BeFree

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