MIR1200 (microRNA 1200)

Gene Basic Information

Gene Basic Information

symbol:
MIR1200
locus group:
non-coding RNA
location:
7p14.2
gene_family:
MicroRNAs
alias symbol:
hsa-mir-1200
alias name:
None
entrez id:
100302113
ensembl gene id:
ENSG00000221325
ucsc gene id:
uc022abw.1
refseq accession:
NR_031604
hgnc_id:
HGNC:35266
approved reserved:
2008-11-03

Chromosome Location

Chromosome Location

7p14.2

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR1200     Wikipedia entry for MIR1200

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR1200:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR1200:           Showing partial SNPs
rs2392476       rs10232938       rs17418220       rs60329391       rs73106657       rs73106658       rs73340222       rs73689699       rs75093471       rs75975550       rs76198676       rs77814495       rs78185366       rs79595925       rs80352916       rs115935740       rs116170386      

Gene Expression

Gene Expression

Tissue expression of MIR1200:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
TCTCCTGAGCCATTCTGAG
58
CCTGACAAATTCCTGAACCA
58
ACTTCTCCTGAGCCATTCTG
59
GACAAATTCCTGAACCAATCTC
57
CTTCTCCTGAGCCATTCTG
57
GACAAATTCCTGAACCAATCTC
57

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR1200 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR1200:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR1200:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

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