MIR1231 (microRNA 1231)

Gene Basic Information

Gene Basic Information

symbol:
MIR1231
locus group:
non-coding RNA
location:
1q32.1
gene_family:
MicroRNAs
alias symbol:
hsa-mir-1231
alias name:
None
entrez id:
100302158
ensembl gene id:
ENSG00000221028
ucsc gene id:
uc021phj.1
refseq accession:
NR_031599
hgnc_id:
HGNC:33921
approved reserved:
2008-01-07

Chromosome Location

Chromosome Location

1q32.1

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR1231     Wikipedia entry for MIR1231

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR1231:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR1231:           Showing partial SNPs
rs2292822       rs2820289       rs4379719       rs59829618       rs73088470       rs75689268       rs75832925       rs76241100       rs76392145       rs112032363       rs114795303       rs114971087       rs115592000       rs115922909       rs116039749       rs116101884       rs116338160      

Gene Expression

Gene Expression

Tissue expression of MIR1231:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
AGGAAAGGGAAGACCAAGG
59
CAAGAACAGACAGGGTAGGG
60
AGGAAAGGGAAGACCAAGG
59
CAAGAACAGACAGGGTAGG
57
AGGAAAGGGAAGACCAAGG
59
AAGAACAGACAGGGTAGGG
58

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR1231 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR1231:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR1231:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Hepatitis B 0.000542884 2 0 BeFree

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Related Publications

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