MIR1288 (microRNA 1288)

Gene Basic Information

Gene Basic Information

symbol:
MIR1288
locus group:
non-coding RNA
location:
17p11.2
gene_family:
MicroRNAs
alias symbol:
hsa-mir-1288
alias name:
None
entrez id:
100302124
ensembl gene id:
ENSG00000221355
ucsc gene id:
uc021tqr.1
refseq accession:
NR_031698
hgnc_id:
HGNC:35363
approved reserved:
2008-11-03

Chromosome Location

Chromosome Location

17p11.2

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR1288     Wikipedia entry for MIR1288

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR1288:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR1288:           Showing partial SNPs
rs1963811       rs1985977       rs2013857       rs2109262       rs3112512       rs3785626       rs73978830       rs73978831       rs114440378       rs115393928       rs115842641       rs117146119       rs137906787       rs141790678       rs142339825       rs142381790       rs143753265      

Gene Expression

Gene Expression

Tissue expression of MIR1288:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
TGATCAGCAGATCAGGACTG
59
GCAGTGGTCTCCAGATCAG
59
TGATCAGCAGATCAGGACTG
59
CAGTGGTCTCCAGATCAGG
59
GATCAGCAGATCAGGACTG
57
CAGTGGTCTCCAGATCAGG
59

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR1288 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR1288:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR1288:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Adenocarcinoma of large intestine 0.000271442 1 0 BeFree
Adenocarcinoma 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Non-Neoplastic Disorder 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree

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