MIR1298 (microRNA 1298)

Gene Basic Information

Gene Basic Information

symbol:
MIR1298
locus group:
non-coding RNA
location:
Xq23
gene_family:
MicroRNAs
alias symbol:
hsa-mir-1298
alias name:
None
entrez id:
100302153
ensembl gene id:
ENSG00000221710
ucsc gene id:
uc022ccz.1
refseq accession:
NR_031578
hgnc_id:
HGNC:35258
approved reserved:
2008-11-03

Chromosome Location

Chromosome Location

Xq23

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR1298     Wikipedia entry for MIR1298

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR1298:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR1298:           Showing partial SNPs
rs782766430       rs782750561       rs782745229       rs782717531       rs782685288       rs782663170       rs782561743       rs782520125       rs782518744       rs782503791       rs782490495       rs782484934       rs782471028       rs782457352       rs782395230       rs782389494       rs782382766      

Gene Expression

Gene Expression

Tissue expression of MIR1298:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
AGGAGTTAAGAGTTCATTCGG
58
ATTGCCAAATAACACAGGGT
58
GAGGAGTTAAGAGTTCATTCGG
59
TTGCCAAATAACACAGGGT
58
GATGTATCCAAGTACCCTGTG
58
AAGTTCAGTCAGTTGCCCA
60

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR1298 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR1298:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR1298:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

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