MIR132 (microRNA 132)

Gene Basic Information

Gene Basic Information

symbol:
MIR132
locus group:
non-coding RNA
location:
17p13.3
gene_family:
MicroRNAs
alias symbol:
hsa-mir-132
alias name:
None
entrez id:
406921
ensembl gene id:
ENSG00000267200
ucsc gene id:
uc010vqt.1
refseq accession:
NR_029674
hgnc_id:
HGNC:31516
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

17p13.3

Gene Summary

Gene Summary

ChineseEnglish

MIR132 encodes a microRNA (miRNA), a short 20–24 nucleotide noncoding RNA that post-transcriptionally regulates gene expression by influencing mRNA stability and translation. miRNAs are transcribed by RNA polymerase II as capped and polyadenylated primary transcripts, cleaved by Drosha into an approximately 70-nucleotide stem-loop precursor, and further processed by cytoplasmic Dicer into mature miRNA and antisense miRNA* products. The mature miRNA is incorporated into RISC, which recognizes target mRNAs through imperfect base pairing and typically represses translation or destabilizes the target mRNA. The RefSeq record represents the predicted MIR132 microRNA stem-loop.

OMIM entry for MIR132     Wikipedia entry for MIR132

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR132:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR132:           Showing partial SNPs
rs2760749       rs2957924       rs3803807       rs3803808       rs111329457       rs115121017       rs117427653       rs149443375       rs183274447       rs184809432       rs186544834       rs189734297       rs201666920       rs372962409       rs373858394       rs375862717       rs527360400      

Gene Expression

Gene Expression

Tissue expression of MIR132:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR132 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR132:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR132:     

Gene Interactions

Gene Interactions

Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Drug-Induced Liver Injury 0.12 1 0 CTD_human
Mammary Neoplasms 0.12 1 0 CTD_human
Rheumatoid Arthritis 0.00272435 1 0 LHGDN
Malignant neoplasm of ovary 0.002367032 1 0 GAD
Osteosarcoma of bone 0.000814326 3 0 BeFree
Osteosarcoma 0.000814326 3 0 BeFree
Neoplasm Metastasis 0.000814326 3 0 BeFree
Stomach Carcinoma 0.000542884 2 0 BeFree
Non-Small Cell Lung Carcinoma 0.000542884 2 0 BeFree
Alzheimer's Disease 0.000542884 2 0 BeFree

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