MIR151B (microRNA 151b)

Gene Basic Information

Gene Basic Information

symbol:
MIR151B
locus group:
non-coding RNA
location:
14q32.2
gene_family:
MicroRNAs
alias symbol:
hsa-mir-151b
alias name:
None
entrez id:
100616247
ensembl gene id:
ENSG00000265154
ucsc gene id:
uc032blj.1
refseq accession:
NR_039601
hgnc_id:
HGNC:41588
approved reserved:
2011-05-02

Chromosome Location

Chromosome Location

14q32.2

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR151B     Wikipedia entry for MIR151B

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR151B:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR151B:           Showing partial SNPs
rs748354       rs8004660       rs12880334       rs36121351       rs61984547       rs61984548       rs61984549       rs71422795       rs71464643       rs73349536       rs73349538       rs78249908       rs111723963       rs116489376       rs116677354       rs117546156       rs138107209      

Gene Expression

Gene Expression

Tissue expression of MIR151B:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
CGAGACACAGAAACAGACAC
59
CCTGGGTTTGTTTGTCTAGAC
59
CCGAGACACAGAAACAGAC
58
CTGGGTTTGTTTGTCTAGACTG
59
TCCCGAGACACAGAAACAG
59
GGGTTTGTTTGTCTAGACTGTG
60

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR151B (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR151B:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR151B:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

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