MIR183 (microRNA 183)

Gene Basic Information

Gene Basic Information

symbol:
MIR183
locus group:
non-coding RNA
location:
7q32.2
gene_family:
MicroRNAs
alias symbol:
hsa-mir-183
alias name:
None
entrez id:
406959
ensembl gene id:
ENSG00000207691
ucsc gene id:
uc003vpd.2
refseq accession:
NR_029615
hgnc_id:
HGNC:31554
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

7q32.2

Gene Summary

Gene Summary

ChineseEnglish

MicroRNAs (miRNAs) are short (20–24 nucleotides) noncoding RNAs that regulate gene expression post-transcriptionally by affecting mRNA stability and translation in multicellular organisms. miRNAs are transcribed by RNA polymerase II as capped and polyadenylated primary transcripts (pri-miRNAs), which may be either protein-coding or noncoding. The primary transcript is cleaved by the ribonuclease III enzyme Drosha to produce an approximately 70-nucleotide stem-loop precursor miRNA (pre-miRNA), which is further processed by cytoplasmic Dicer ribonuclease to yield mature miRNA and antisense miRNA star (*miRNA) products. Mature miRNAs are incorporated into RNA-induced silencing complexes (RISCs), which recognize target mRNAs through imperfect base pairing with the miRNA and most often cause translational repression or destabilization of the target mRNA. RefSeq represents the predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]

OMIM entry for MIR183     Wikipedia entry for MIR183

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR183:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR183:           Showing partial SNPs
rs4335057       rs6947908       rs6947939       rs7811300       rs12538588       rs13231740       rs17557722       rs41274239       rs41281222       rs57560217       rs72631833       rs73159662       rs73487512       rs74994806       rs75051943       rs75434827       rs75906219      

Gene Expression

Gene Expression

Tissue expression of MIR183:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GTAGAATTCACTGTGAACAGTCTC
60
TCTGCTCTGTTTATGGCCC
60
GGTAGAATTCACTGTGAACAGTC
60
CTGCTCTGTTTATGGCCCT
60
GTTCTGTGTATGGCACTGG
59
CTTCGGTAATTCACTGACTGAG
59

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR183 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR183:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR183:     

Gene Interactions

Gene Interactions

Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Noise-induced hearing loss 0.12 1 0 CTD_human
Liver Neoplasms, Experimental 0.12 1 0 CTD_human
Myocardial Reperfusion Injury 0.12 1 0 CTD_human
Fatty Liver 0.12 1 0 CTD_human
Neoplasm Metastasis 0.005981653 12 0 BeFree_LHGDN
Secondary malignant neoplasm of lymph node 0.001357209 5 0 BeFree
Liver carcinoma 0.001085767 4 0 BeFree
Malignant neoplasm of lung 0.001085767 4 0 BeFree
Osteosarcoma 0.001085767 4 0 BeFree
Osteosarcoma of bone 0.001085767 4 0 BeFree

Related Publications

Related Publications

Identification of miR136, miR155, and miR183 in Vascular Calcification in Human Peripheral Arteries.
Le Corvec T, Burgaud M, Steenman M, Tesfaye RA, Gouëffic Y, Maurel B, Quillard T Int J Mol Sci IF: 3.226 2025-09-25
Families of microRNAs Expressed in Clusters Regulate Cell Signaling in Cervical Cancer.
Servín-González Luis Steven, Granados-López Angelica Judith, López Jesús Adrián Int J Mol Sci IF: 3.226 2016-03-14
A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer.
Wang Lin, Zhu Miao-Jun, Ren Ai-Min, Wu Hong-Fei, Han Wu-Mei, Tan Ruo-Ying, Tu Rui-Qin PLoS One IF: 2.6 2015-10-19
Gliomas display a microRNA expression profile reminiscent of neural precursor cells.
Lavon Iris, Zrihan Daniel, Granit Avital, Einstein Ofira, Fainstein Nina, Cohen Malkiel A, Cohen Mikhal A, Zelikovitch Bracha, Shoshan Yigal, Spektor Sergei, Reubinoff Benjamin E, Felig Yakov, Gerlitz Offer, Ben-Hur Tamir, Smith Yohav, Siegal Tali Neuro Oncol IF: 13.1 2010-07-15

Related Services

Related Services

Comments

Comments

Loading comments...

Log in to post comments Log In Sign Up

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2