MIR184 (microRNA 184)

Gene Basic Information

Gene Basic Information

symbol:
MIR184
locus group:
non-coding RNA
location:
15q25.1
gene_family:
MicroRNAs
alias symbol:
hsa-mir-184
alias name:
None
entrez id:
406960
ensembl gene id:
ENSG00000207695
ucsc gene id:
uc010uni.2
refseq accession:
NR_029705
hgnc_id:
HGNC:31555
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

15q25.1

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR184     Wikipedia entry for MIR184

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR184:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR184:           Showing partial SNPs
rs12324079       rs12903401       rs28494584       rs28756822       rs34027892       rs41280052       rs58249183       rs59404089       rs62014763       rs73470441       rs77371888       rs78158413       rs78990609       rs79962446       rs111386548       rs112085210       rs112994281      

Gene Expression

Gene Expression

Tissue expression of MIR184:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR184 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR184:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR184:     

Gene Interactions

Gene Interactions

Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
EDICT SYNDROME 0.241085767 4 0 BeFree_CLINVAR_ORPHANET
Obesity 0.12 1 0 CTD_human
Squamous cell carcinoma 0.003267234 3 0 BeFree_LHGDN
Keratoconus 0.000814326 3 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
CATARACT, ANTERIOR POLAR 0.000542884 2 0 BeFree
Glioma 0.000542884 2 0 BeFree
Liver carcinoma 0.000542884 2 0 BeFree
Axial myopia 0.000271442 1 0 BeFree
Diabetes 0.000271442 1 0 BeFree

Related Publications

Related Publications

The Genetic and Epigenetic Architecture of Keratoconus: Emerging Pathways and Clinical Implications.
Cappellani F, Capobianco M, Visalli F, Mazzotta C, D'Esposito F, Tognetto D, Gagliano C, Zeppieri M Genes (Basel) IF: 3.600 2026-01-06
Rare variants in MIR184 are a novel genetic cause of Fuchs endothelial corneal dystrophy.
Abreu Costa M, Sadan AN, Bhattacharyya N, Chai N, Zarouchlioti C, Liu S, Szabo A, Murphy C, Dudakova L, Muthusamy K, Skalicka P, Moghul I, Pontikos N, Liskova P, Tuft SJ, Davidson AE Genet Med IF: 6.2 2025-11-00
C.57 C > T Mutation in MIR 184 is Responsible for Congenital Cataracts and Corneal Abnormalities in a Five-generation Family from Galicia, Spain.
Bykhovskaya Yelena, Caiado Canedo Ana L, Wright Kenneth W, Rabinowitz Yaron S Ophthalmic Genet IF: 1.0 2016-04-01
Screening of the Seed Region of MIR184 in Keratoconus Patients from Saudi Arabia.
Abu-Amero Khaled K, Helwa Inas, Al-Muammar Abdulrahman, Strickland Shelby, Hauser Michael A, Allingham R Rand, Liu Yutao Biomed Res Int IF: 2.9 2016-06-20
Screening for MIR184 Mutations in Iranian Patients with Keratoconus.
Farzadfard Azad, Nassiri Nader, Moghadam Tayebeh Nekuie, Paylakhi Seyed Hassan, Elahi Elahe J Ophthalmic Vis Res IF: 1.4 2016-05-19
MicroRNAs: new candidates for the regulation of the human cumulus-oocyte complex.
Assou S, Al-edani T, Haouzi D, Philippe N, Lecellier C-H, Piquemal D, Commes T, Aït-Ahmed O, Dechaud H, Hamamah S Hum Reprod IF: 6.8 2014-06-16
Mutational analysis of MIR184 in sporadic keratoconus and myopia.
Lechner Judith, Bae Ha Ae, Guduric-Fuchs Jasenka, Rice Aine, Govindarajan Gowthaman, Siddiqui Salina, Abi Farraj Layal, Yip Shea Ping, Yap Maurice, Das Manoranjan, Souzeau Emmanuelle, Coster Doug, Mills Richard A, Lindsay Richard, Phillips Tony, Mitchell Paul, Ali Manir, Inglehearn Chris F, Sundaresan Periasamy, Craig Jamie E, Simpson David A, Burdon Kathryn P, Willoughby Colin E Invest Ophthalmol Vis Sci IF: 5.5 2013-09-30
Insights into keratoconus from a genetic perspective.
Burdon Kathryn P, Vincent Andrea L Clin Exp Optom IF: 1.6 2013-09-09
Mutation altering the miR-184 seed region causes familial keratoconus with cataract.
Hughes Anne E, Bradley Declan T, Campbell Malcolm, Lechner Judith, Dash Durga P, Simpson David A, Willoughby Colin E Am J Hum Genet IF: 7.7 2012-02-21

Related Services

Related Services

Comments

Comments

Loading comments...

Log in to post comments Log In Sign Up

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2