MIR197 (microRNA 197)

Gene Basic Information

Gene Basic Information

symbol:
MIR197
locus group:
non-coding RNA
location:
1p13.3
gene_family:
MicroRNAs
alias symbol:
hsa-mir-197
alias name:
None
entrez id:
406974
ensembl gene id:
ENSG00000284443
ucsc gene id:
uc010ovq.1
refseq accession:
NR_029583
hgnc_id:
HGNC:31569
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

1p13.3

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR197     Wikipedia entry for MIR197

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR197:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR197:           Showing partial SNPs
rs505303       rs1889470       rs17024132       rs17648684       rs71577006       rs74113948       rs111351338       rs111978115       rs112644286       rs113172998       rs116233808       rs137967845       rs138384957       rs140943578       rs140998698       rs141677608       rs142872331      

Gene Expression

Gene Expression

Tissue expression of MIR197:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR197 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR197:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR197:     

Gene Interactions

Gene Interactions

Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Neoplasm Metastasis 0.120271442 2 0 BeFree_CTD_human
Fatty Liver 0.12 1 0 CTD_human
Myocardial Reperfusion Injury 0.12 1 0 CTD_human
Malignant neoplasm of ovary 0.002367032 1 0 GAD
Non-Small Cell Lung Carcinoma 0.000814326 3 0 BeFree
Malignant neoplasm of lung 0.000542884 2 0 BeFree
Metabolic Syndrome X 0.000542884 2 0 BeFree
Carcinoma of lung 0.000542884 2 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Thyroid carcinoma 0.000271442 1 0 BeFree

Related Publications

Related Publications

The roles and pathways of Hsa_circ_0000285 in cancer: a potential target for cancer therapy.
Lv Y, Li D, Zhang QX, Zeng T, Luo XY, Guo Q, Ren QY Cell Div IF: 3.909 2026-03-11

Related Services

Related Services

Comments

Comments

Loading comments...

Log in to post comments Log In Sign Up

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2