MIR203A (microRNA 203a)

Gene Basic Information

Gene Basic Information

symbol:
MIR203A
locus group:
non-coding RNA
location:
14q32.33
gene_family:
MicroRNAs
alias symbol:
hsa-mir-203
alias name:
None
entrez id:
406986
ensembl gene id:
ENSG00000207568
ucsc gene id:
None
refseq accession:
NR_029620
hgnc_id:
HGNC:31581
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

14q32.33

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR203A     Wikipedia entry for MIR203A

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR203A:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR203A:           Showing partial SNPs
rs750062       rs35459432       rs56252815       rs61997624       rs74087137       rs139042166       rs141491119       rs146176986       rs182049888       rs183789316       rs186716953       rs187641322       rs189746444       rs192443540       rs368091593       rs369521735       rs374712314      

Gene Expression

Gene Expression

Tissue expression of MIR203A:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GGTCCAGTGGTTCTTAACAG
58
GTCTAGTGGTCCTAAACATTTCAC
60
GTGGTTCTTAACAGTTCAACAG
58
GTCTAGTGGTCCTAAACATTTCAC
60

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR203A (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR203A:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR203A:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Neoplasm Metastasis 0.122714419 11 0 BeFree_CTD_human
Carcinogenesis 0.120542884 2 0 BeFree_CTD_human
Psoriasis 0.002995792 2 0 BeFree_LHGDN
Esophageal carcinoma 0.001900093 7 0 BeFree
Squamous cell carcinoma of esophagus 0.001900093 7 0 BeFree
Malignant neoplasm of esophagus 0.001628651 6 0 BeFree
Esophageal Neoplasms 0.001628651 6 0 BeFree
Squamous cell carcinoma 0.001357209 5 0 BeFree
Malignant tumor of cervix 0.001357209 5 0 BeFree
melanoma 0.001357209 5 0 BeFree

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