MIR24-2 (microRNA 24-2)

Gene Basic Information

Gene Basic Information

symbol:
MIR24-2
locus group:
non-coding RNA
location:
19p13.12
gene_family:
MicroRNAs
alias symbol:
hsa-mir-24-2
alias name:
None
entrez id:
407013
ensembl gene id:
ENSG00000284387
ucsc gene id:
uc060ujv.1
refseq accession:
NR_029497
hgnc_id:
HGNC:31608
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

19p13.12

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR24-2     Wikipedia entry for MIR24-2

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR24-2:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR24-2:           Showing partial SNPs
rs345638       rs895819       rs8101375       rs10422126       rs10423627       rs11671784       rs36116239       rs41276896       rs62122063       rs73922780       rs73922782       rs74523123       rs76619236       rs77630419       rs78494746       rs111251582       rs114246707      

Gene Expression

Gene Expression

Tissue expression of MIR24-2:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR24-2 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR24-2:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR24-2:     

Gene Interactions

Gene Interactions

Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Mammary Neoplasms 0.120271442 1 0 BeFree_CTD_human
Malignant neoplasm of breast 0.002909916 3 0 BeFree_GAD
Schizophrenia 0.002367032 1 0 GAD
Breast Carcinoma 0.000542884 2 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lymph node 0.000271442 1 0 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
Acute leukemia 0.000271442 1 0 BeFree

Related Publications

Related Publications

Involvement of microRNA-24 and DNA methylation in resistance of nasopharyngeal carcinoma to ionizing radiation.
Wang Sumei, Zhang Rong, Claret Francois X, Yang Huiling Mol Cancer Ther IF: 6.9 2015-08-11
CTNNB1 gene mutations, pituitary transcription factors, and MicroRNA expression involvement in the pathogenesis of adamantinomatous craniopharyngiomas.
Campanini Marina Lanciotti, Colli Leandro Machado, Paixao Beatriz Maria Carvalho, Cabral Tatiana Pereira Freitas, Amaral Fernando Colbari, Machado Helio Rubens, Neder Luciano Serafin, Saggioro Fabiano, Moreira Ayrton Custodio, Antonini Sonir Roberto Rauber, de Castro Margaret Horm Cancer IF: nan 2011-12-19
A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness.
Lee Sung-Hun, Chen Tsai-Yu, Dhar Shilpa S, Gu Bingnan, Chen Kaifu, Kim Young Zoon, Li Wei, Lee Min Gyu Nucleic Acids Res IF: 15.0 0000-00-00

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