MIR26A2 (microRNA 26a-2)

Gene Basic Information

Gene Basic Information

symbol:
MIR26A2
locus group:
non-coding RNA
location:
12q14.1
gene_family:
MicroRNAs
alias symbol:
hsa-mir-26a-2
alias name:
None
entrez id:
407016
ensembl gene id:
ENSG00000207789
ucsc gene id:
uc001sqn.2
refseq accession:
NR_029847
hgnc_id:
HGNC:31611
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

12q14.1

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR26A2     Wikipedia entry for MIR26A2

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR26A2:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR26A2:           Showing partial SNPs
rs870392       rs871871       rs35406632       rs41292017       rs78073833       rs78914828       rs111589440       rs111857325       rs113514774       rs118027518       rs139687109       rs139739010       rs139907421       rs140762395       rs143008068       rs144506463       rs145194107      

Gene Expression

Gene Expression

Tissue expression of MIR26A2:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
TGGCTGGATTCAAGTAATCCA
60
GTAATCAAGAATAGGCCTCACAG
59
TGGCTGGATTCAAGTAATCC
58
GTAATCAAGAATAGGCCTCACAG
59
GTGGCTGGATTCAAGTAATCC
59
TAATCAAGAATAGGCCTCACAG
58

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR26A2 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR26A2:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR26A2:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

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Related Publications

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