MIR3116-2 (microRNA 3116-2)

Gene Basic Information

Gene Basic Information

symbol:
MIR3116-2
locus group:
non-coding RNA
location:
1p31.3
gene_family:
MicroRNAs
alias symbol:
hsa-mir-3116-2
alias name:
None
entrez id:
100422946
ensembl gene id:
ENSG00000283690
ucsc gene id:
uc031ucn.1
refseq accession:
NR_036059
hgnc_id:
HGNC:38318
approved reserved:
2010-04-30

Chromosome Location

Chromosome Location

1p31.3

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR3116-2     Wikipedia entry for MIR3116-2

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR3116-2:[NCBI]
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Gene Variants

Gene Variants

SNP variants of MIR3116-2:           Showing partial SNPs
rs3934216       rs7537716       rs11207898       rs11207899       rs17097039       rs17379217       rs74076514       rs77502735       rs77582677       rs78228749       rs80346568       rs113176396       rs115331189       rs116556566       rs141963809       rs142521914       rs142572603      

Gene Expression

Gene Expression

Tissue expression of MIR3116-2:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
ATTGAGTCCCTACTATGTTCCA
59
GTCCCTACTATGTTCCAGGC
60
TATTGAGTCCCTACTATGTTCCAG
59
TCCCTACTATGTTCCAGGC
58
CTTTATTGAGTCCCTACTATGTTCC
59
CTACTATGTTCCAGGCACC
57

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR3116-2 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR3116-2:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR3116-2:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

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