MIR3182 (microRNA 3182)

symbol
MIR3182
locus group
non-coding RNA
location
16q23.3
gene_family
MicroRNAs
alias symbol
hsa-mir-3182
alias name
None
entrez id
100422853
ensembl gene id
ENSG00000263785
ucsc gene id
uc021tlx.1
refseq accession
NR_036147
hgnc_id
HGNC:38317
approved reserved
2010-04-30
16q23.3
ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Nucleotide sequence of MIR3182:[NCBI]
Loading Gene Browser...
SNP variants of MIR3182:           Showing partial SNPs
rs4782539       rs4782540       rs4782541       rs4782806       rs4782807       rs7188802       rs7189644       rs7194653       rs7195083       rs8062929       rs11449551       rs12922481       rs12922800       rs12923171       rs35792057       rs62042278       rs71390969      
Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GCTGCTTCTGTAGTGTAGTC
58
TGCTCTATGATCCAACCCA
58
CTGCTTCTGTAGTGTAGTCC
57
CTGCTCTATGATCCAACCCA
59
CTGCTTCTGTAGTGTAGTCC
57
CTGCTCTATGATCCAACCC
57
circUBAP2 exacerbates malignant capabilities of NSCLC by targeting KLF4 through miR-3182 modulation.
Zheng G, Huang J, Chen W, You P, Ding Y, Tu P Aging (Albany NY) IF: 3.9 2021-00-19

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