MIR320B1 (microRNA 320b-1)

Gene Basic Information

Gene Basic Information

symbol:
MIR320B1
locus group:
non-coding RNA
location:
1p13.1
gene_family:
MicroRNAs
alias symbol:
hsa-mir-320b-1
alias name:
None
entrez id:
100302117
ensembl gene id:
ENSG00000211543
ucsc gene id:
uc021osk.1
refseq accession:
NR_031564
hgnc_id:
HGNC:35247
approved reserved:
2008-11-03

Chromosome Location

Chromosome Location

1p13.1

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR320B1     Wikipedia entry for MIR320B1

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR320B1:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR320B1:           Showing partial SNPs
rs599563       rs676886       rs699790       rs699791       rs699792       rs699793       rs12740491       rs71668603       rs72697354       rs75063835       rs78281234       rs111421358       rs112649694       rs114782906       rs116147054       rs116453423       rs138556894      

Gene Expression

Gene Expression

Tissue expression of MIR320B1:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR320B1 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR320B1:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR320B1:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
Dong Jing, Wyss Annah, Yang Jingyun, Price T Ryan, Nicolas Aude, Nalls Michael, Tranah Greg, Franceschini Nora, Xu Zongli, Schulte Claudia, Alonso Alvaro, Cummings Steven R, Fornage Myriam, Zaykin Dmitri, Li Leping, Huang Xuemei, Kritchevsky Stephen, Liu Yongmei, Gasser Thomas, Wilson Robert S, De Jager Philip L, Singleton Andrew B, Pinto Jayant M, Harris Tamara, Mosley Thomas H, Bennett David A, London Stephanie, Yu Lei, Chen Honglei Mol Neurobiol IF: 5.5 0000-00-00

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