MIR331 (microRNA 331)

Gene Basic Information

Gene Basic Information

symbol:
MIR331
locus group:
non-coding RNA
location:
12q22
gene_family:
MicroRNAs
alias symbol:
hsa-mir-331
alias name:
None
entrez id:
442903
ensembl gene id:
ENSG00000199172
ucsc gene id:
uc001tea.2
refseq accession:
NR_029895
hgnc_id:
HGNC:31772
approved reserved:
2004-07-22

Chromosome Location

Chromosome Location

12q22

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR331     Wikipedia entry for MIR331

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR331:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR331:           Showing partial SNPs
rs901895       rs11107972       rs11107973       rs35321521       rs55759600       rs75399294       rs76422324       rs76644940       rs78312394       rs79438507       rs80111105       rs111546589       rs112310009       rs113105533       rs113623334       rs113883836       rs116931345      

Gene Expression

Gene Expression

Tissue expression of MIR331:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
TTCTAGGTATGGTCCCAGG
58
TGGTTCTAGGATAGGCCCA
59
GTTCTAGGTATGGTCCCAGG
59
GGTTCTAGGATAGGCCCAG
59
TGTTCTAGGTATGGTCCCAG
58
GTTCTAGGATAGGCCCAGG
59

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR331 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR331:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR331:     

Gene Interactions

Gene Interactions

Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Liver Neoplasms, Experimental 0.12 1 0 CTD_human
Myocardial Reperfusion Injury 0.12 1 0 CTD_human
Precancerous Conditions 0.12 1 0 CTD_human
Noise-induced hearing loss 0.12 1 0 CTD_human
Glioblastoma 0.000542884 2 0 BeFree
Stomach Carcinoma 0.000542884 2 0 BeFree
Malignant neoplasm of stomach 0.000542884 2 0 BeFree
Liver carcinoma 0.000542884 2 0 BeFree
Hepatitis B 0.000271442 1 0 BeFree
Glioblastoma Multiforme 0.000271442 1 0 BeFree

Related Publications

Related Publications

Identification of distinct gene and miRNA expression profiles in severe early-onset COPD providing novel insights in disease pathogenesis.
Bekker NJ, Van Nijnatten JL, Horvatovich PL, Wolters JC, Guryev V, Karp T, Kooistra W, Reinders-Luinge M, Woldhuis RR, Timens W, Faiz A, van den Berge M, Brandsma CA Thorax IF: 9.1 2026-07-21

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