MIR362 (microRNA 362)

Gene Basic Information

Gene Basic Information

symbol:
MIR362
locus group:
non-coding RNA
location:
Xp11.23
gene_family:
MicroRNAs
alias symbol:
hsa-mir-362
alias name:
None
entrez id:
574030
ensembl gene id:
ENSG00000208015
ucsc gene id:
uc022bwh.2
refseq accession:
NR_029850
hgnc_id:
HGNC:32022
approved reserved:
2005-06-30

Chromosome Location

Chromosome Location

Xp11.23

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR362     Wikipedia entry for MIR362

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR362:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR362:           Showing partial SNPs
rs782805535       rs782789700       rs782785883       rs782773443       rs782749442       rs782748998       rs782740726       rs782715546       rs782632456       rs782631587       rs782631492       rs782611023       rs782577823       rs782518683       rs782517600       rs782495046       rs782493811      

Gene Expression

Gene Expression

Tissue expression of MIR362:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR362 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR362:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR362:     

Gene Interactions

Gene Interactions

Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Myocardial Reperfusion Injury 0.12 1 0 CTD_human
Malignant neoplasm of stomach 0.000542884 2 0 BeFree
Stomach Carcinoma 0.000542884 2 0 BeFree
Colorectal Carcinoma 0.000542884 2 0 BeFree
Neoplasm Metastasis 0.000542884 2 0 BeFree
Colorectal Cancer 0.000542884 2 0 BeFree
Stage 4S neuroblastoma 0.000271442 1 0 BeFree
melanoma 0.000271442 1 0 BeFree
Central neuroblastoma 0.000271442 1 0 BeFree
Disseminated neuroblastoma 0.000271442 1 0 BeFree

Related Publications

Related Publications

Biologic profiling of lymph node negative breast cancers by means of microRNA expression.
Janssen Emiel A M, Slewa Aida, Gudlaugsson Einar, Jonsdottir Kristin, Skaland Ivar, Søiland Håvard, Baak Jan P A Mod Pathol IF: 6.6 2011-03-21

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