MIR3678 (microRNA 3678)

Gene Basic Information

Gene Basic Information

symbol:
MIR3678
locus group:
non-coding RNA
location:
17q25.1
gene_family:
MicroRNAs
alias symbol:
hsa-mir-3678
alias name:
None
entrez id:
100500841
ensembl gene id:
ENSG00000264511
ucsc gene id:
uc021ucz.1
refseq accession:
NR_037449
hgnc_id:
HGNC:38891
approved reserved:
2010-09-15

Chromosome Location

Chromosome Location

17q25.1

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR3678     Wikipedia entry for MIR3678

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR3678:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR3678:           Showing partial SNPs
rs7220246       rs12943902       rs35863858       rs55984901       rs56007395       rs56272997       rs56299118       rs56347701       rs61764585       rs61764588       rs61764589       rs61764590       rs61764591       rs61764592       rs61764593       rs61764594       rs73996044      

Gene Expression

Gene Expression

Tissue expression of MIR3678:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GCTGTGTTGAATGATTGGTG
58
CCGTACAAACTCTGCAGTG
59
CCGTACAAACTCTGCTGTG
59
GCAGTGATTCAATCAATGAGC
58
CTGTGTTGAATGATTGGTGAG
58
CCGTACAAACTCTGCAGTG
59

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR3678 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR3678:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR3678:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

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