MIR3681 (microRNA 3681)

Gene Basic Information

Gene Basic Information

symbol:
MIR3681
locus group:
non-coding RNA
location:
2p24.3
gene_family:
MicroRNAs
alias symbol:
hsa-mir-3681
alias name:
None
entrez id:
100500884
ensembl gene id:
ENSG00000264089
ucsc gene id:
uc032nev.1
refseq accession:
NR_037452
hgnc_id:
HGNC:38994
approved reserved:
2010-09-15

Chromosome Location

Chromosome Location

2p24.3

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR3681     Wikipedia entry for MIR3681

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR3681:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR3681:           Showing partial SNPs
rs971885       rs4669827       rs6432269       rs10199976       rs10200170       rs10202729       rs10210767       rs11685038       rs11686692       rs12476454       rs13407546       rs13407781       rs13429326       rs73194402       rs74767360       rs76761049       rs79394935      

Gene Expression

Gene Expression

Tissue expression of MIR3681:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GTGGATGATGCACTCTGTG
59
CTTCCAGTAGTGGATGAAGCA
60
GTGGATGATGCACTCTGTG
59
CTTCCAGTAGTGGATGAAGC
58
AGTAGTGGATGATGCACTCTG
60
CAGTAGTGGATGAAGCACTG
58

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR3681 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR3681:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR3681:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

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