MIR3914-1 (microRNA 3914-1)
- symbol:
- MIR3914-1
- locus group:
- non-coding RNA
- location:
- 7q11.22
- gene_family:
- MicroRNAs
- alias symbol:
- hsa-mir-3914-1
- alias name:
- None
- entrez id:
- 100500836
- ensembl gene id:
- ENSG00000265878
- ucsc gene id:
- None
- refseq accession:
- NR_037477
- hgnc_id:
- HGNC:38993
- approved reserved:
- 2010-09-15
MicroRNAs (miRNAs) are short (20–24 nucleotide) noncoding RNAs that regulate gene expression post-transcriptionally in multicellular organisms by affecting mRNA stability and translation. miRNAs are transcribed by RNA polymerase II as capped and polyadenylated primary transcripts (pri-miRNAs), which may be protein-coding or noncoding. Pri-miRNAs are cleaved by the ribonuclease III enzyme Drosha to produce approximately 70-nucleotide stem-loop precursor miRNAs (pre-miRNAs), which are further processed by cytoplasmic Dicer to yield mature miRNA and antisense miRNA star (miRNA*) products. Mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational repression or destabilization of the target mRNA. The RefSeq record represents a predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]
Gene Ontology
Subcellular localization of MIR3914-1 (and its protein):
- plasma membrane
- cytoplasm
- extracellular
- golgi
- vesicle
- cytoskeleton
- endoplasmic reticulum
- nucleus
- endosome
- lysosome
- mitochondrion
Gene Ontology (GO) terms for MIR3914-1:
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