MIR3923 (microRNA 3923)

symbol:
MIR3923
locus group:
non-coding RNA
location:
3p12.3
gene_family:
MicroRNAs
alias symbol:
hsa-mir-3923
alias name:
None
entrez id:
100500877
ensembl gene id:
ENSG00000265193
ucsc gene id:
uc032rsd.1
refseq accession:
NR_037488
hgnc_id:
HGNC:38978
approved reserved:
2010-09-15
3p12.3
ChineseEnglish

MicroRNAs (miRNAs) are short (20–24 nucleotides) noncoding RNAs that participate in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNA genes are transcribed by RNA polymerase II as parts of capped and polyadenylated primary transcripts (pri-miRNAs), which can be protein-coding or noncoding. The primary transcript is cleaved by the ribonuclease III enzyme Drosha to produce an approximately 70-nucleotide stem-loop precursor miRNA (pre-miRNA), which cytoplasmic Dicer further cleaves to generate mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing and most commonly leads to translational inhibition or destabilization of the target mRNA. RefSeq represents the predicted microRNA stem-loop for MIR3923. [Provided by RefSeq, Sep 2009]

Nucleotide sequence of MIR3923:[NCBI]
Loading Gene Browser...
SNP variants of MIR3923:           Showing partial SNPs
rs6548622       rs6548623       rs9810213       rs9840659       rs9858332       rs10154835       rs11918927       rs28604347       rs28662218       rs56978603       rs62257609       rs62257610       rs72900071       rs80043357       rs111509626       rs114048702       rs114104851      

Tissue expression of MIR3923:    [UniProt]

Gene expression across tissues
Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GGTAGAGTGAGCTCTAATCCA
59
AGTAGAGTGAGCCCTAATCC
58
GGTAGAGTGAGCTCTAATCCA
59
GTAGAGTGAGCCCTAATCCA
58
GGTAGAGTGAGCTCTAATCCA
59
CCCTAATCCAACATTACTAGTTTCC
59
      No data available

Subcellular localization of MIR3923 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR3923:

microRNAs potentially regulating MIR3923:     

Loading…
Interacting Gene Interaction Source/Score
Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree

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