MIR3976 (microRNA 3976)

Gene Basic Information

Gene Basic Information

symbol:
MIR3976
locus group:
non-coding RNA
location:
18p11.31
gene_family:
MicroRNAs
alias symbol:
hsa-mir-3976
alias name:
None
entrez id:
100616244
ensembl gene id:
ENSG00000272380
ucsc gene id:
uc021ugp.1
refseq accession:
NR_039772
hgnc_id:
HGNC:41578
approved reserved:
2011-05-02

Chromosome Location

Chromosome Location

18p11.31

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR3976     Wikipedia entry for MIR3976

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR3976:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR3976:           Showing partial SNPs
rs7244922       rs7507008       rs7507032       rs9954653       rs9956037       rs9956953       rs9965310       rs9966028       rs11081216       rs28626301       rs28684980       rs35118792       rs62076814       rs72855836       rs72855838       rs72855840       rs72855841      

Gene Expression

Gene Expression

Tissue expression of MIR3976:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
ATATTGGAGTTGGACTGCAG
58
CAGTAAAGGTTACATCAGCAC
57
TATTGGAGTTGGACTGCAGG
60
GCAGTAAAGGTTACATCAGCA
59
TATTGGAGTTGGACTGCAG
57
CAGTAAAGGTTACATCAGCAC
57

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR3976 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR3976:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR3976:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Pancreatic carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of pancreas 0.000271442 1 0 BeFree

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