MIR4252 (microRNA 4252)
- symbol:
- MIR4252
- locus group:
- non-coding RNA
- location:
- 1p36.31
- gene_family:
- MicroRNAs
- alias symbol:
- hsa-mir-4252
- alias name:
- None
- entrez id:
- 100422975
- ensembl gene id:
- ENSG00000265392
- ucsc gene id:
- uc021ofo.1
- refseq accession:
- NR_036218
- hgnc_id:
- HGNC:38384
- approved reserved:
- 2010-04-30
MicroRNAs (miRNAs) are short (20–24 nucleotide) noncoding RNAs that regulate gene expression post-transcriptionally in multicellular organisms by affecting mRNA stability and translation. They are transcribed by RNA polymerase II as parts of capped and polyadenylated primary transcripts (pri-miRNAs), which can be protein-coding or noncoding. The primary transcript is cleaved by Drosha ribonuclease III to produce an approximately 70-nucleotide stem-loop precursor miRNA (pre-miRNA), which cytoplasmic Dicer further cleaves to yield mature miRNA and antisense star miRNA (miRNA*). Mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing and usually leads to translational inhibition or destabilization of the target mRNA. MIR4252 is represented in RefSeq as a predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]
Gene Ontology
Subcellular localization of MIR4252 (and its protein):
- plasma membrane
- cytoplasm
- extracellular
- golgi
- vesicle
- cytoskeleton
- endoplasmic reticulum
- nucleus
- endosome
- lysosome
- mitochondrion
Gene Ontology (GO) terms for MIR4252:
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