MIR4275 (microRNA 4275)
- symbol:
- MIR4275
- locus group:
- non-coding RNA
- location:
- 4p15.1
- gene_family:
- MicroRNAs
- alias symbol:
- hsa-mir-4275
- alias name:
- None
- entrez id:
- 100422937
- ensembl gene id:
- ENSG00000283275
- ucsc gene id:
- None
- refseq accession:
- NR_036237
- hgnc_id:
- HGNC:38293
- approved reserved:
- 2010-04-30
MicroRNAs (miRNAs) are short (20–24 nucleotide) noncoding RNAs that post-transcriptionally regulate gene expression in multicellular organisms by affecting mRNA stability and translation. They are transcribed by RNA polymerase II as capped and polyadenylated primary transcripts (pri-miRNAs), which may be protein-coding or noncoding. Drosha ribonuclease III cleaves the primary transcript to produce an approximately 70-nucleotide stem-loop precursor miRNA (pre-miRNA), which cytoplasmic Dicer ribonuclease further processes into mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing and most often causes translational repression or destabilization of the target mRNA. The RefSeq entry represents MIR4275 as a predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]
Gene Ontology
Subcellular localization of MIR4275 (and its protein):
- plasma membrane
- cytoplasm
- extracellular
- golgi
- vesicle
- cytoskeleton
- endoplasmic reticulum
- nucleus
- endosome
- lysosome
- mitochondrion
Gene Ontology (GO) terms for MIR4275:
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