MIR4284 (microRNA 4284)

Gene Basic Information

Gene Basic Information

symbol:
MIR4284
locus group:
non-coding RNA
location:
7q11.23
gene_family:
MicroRNAs
alias symbol:
hsa-mir-4284
alias name:
None
entrez id:
100422948
ensembl gene id:
ENSG00000265724
ucsc gene id:
uc022afw.1
refseq accession:
NR_036247
hgnc_id:
HGNC:38322
approved reserved:
2010-04-30

Chromosome Location

Chromosome Location

7q11.23

Gene Summary

Gene Summary

ChineseEnglish

MicroRNAs (miRNAs) are short, 20–24 nucleotide noncoding RNAs that participate in post-transcriptional regulation of gene expression by affecting mRNA stability and translation in multicellular organisms. miRNAs are transcribed by RNA polymerase II as capped and polyadenylated primary transcripts (pri-miRNAs), which may be protein-coding or noncoding. Pri-miRNAs are cleaved by the RNase III enzyme Drosha to produce approximately 70-nucleotide stem-loop precursor miRNAs (pre-miRNAs), which are further processed by cytoplasmic Dicer to yield mature miRNA and antisense miRNA* products. The mature miRNA is incorporated into the RNA-induced silencing complex (RISC), where it recognizes target mRNAs through imperfect base pairing with the miRNA, most often leading to translational repression or destabilization of the target mRNA. This RefSeq represents the predicted microRNA stem-loop. Provided by RefSeq, September 2009.

OMIM entry for MIR4284     Wikipedia entry for MIR4284

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR4284:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR4284:           Showing partial SNPs
rs941298       rs941299       rs10229375       rs10232729       rs11973069       rs11973898       rs28452991       rs73364306       rs74656420       rs80042768       rs111296530       rs111645856       rs117943116       rs142300739       rs142352692       rs145087813       rs148336154      

Gene Expression

Gene Expression

Tissue expression of MIR4284:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR4284 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR4284:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR4284:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Invasive Carcinoma 0.000271442 1 0 BeFree
Pediatric ulcerative colitis 0.000271442 1 0 BeFree
Colitis 0.000271442 1 0 BeFree
Glioblastoma 0.000271442 1 0 BeFree

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