MIR4315-1 (microRNA 4315-1)

symbol
MIR4315-1
locus group
non-coding RNA
location
17q21.31
gene_family
MicroRNAs
alias symbol
hsa-mir-4315-1
alias name
None
entrez id
100423004
ensembl gene id
ENSG00000284055
ucsc gene id
-
refseq accession
NR_036199
hgnc_id
HGNC:38342
approved reserved
2010-04-30
17q21.31
ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Nucleotide sequence of MIR4315-1:[NCBI]
Loading Gene Browser...
SNP variants of MIR4315-1:           Showing partial SNPs
rs2090848       rs2521859       rs2684710       rs2684711       rs7218394       rs11079565       rs12452076       rs12452273       rs71238846       rs71373588       rs76487603       rs111658952       rs114638526       rs138787527       rs138940893       rs138951599       rs139188329      

Loading comments...

Log in to post comments Log In Sign Up

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]